Intrauterine insemination, or IUI, refers to the placement of washed or processed sperm directly into the uterus, just where the fallopian tubes begin. It is relatively simple treatment for infertility designed to get more sperm to meet the egg. IUI is performed near the time you ovulate. IUI is recommended when there is a problem with the male partner’s sperm, such as low sperm count or his sperm do not move well. IUI may also be useful if there is a problem with a woman’s cervical mucus. IUI may also be an option when the man is not able to ejaculate inside the vagina because of erectile dysfunction, premature ejaculation, or other medical conditions. Sometimes, IUI may also be recommended if the infertility is unexplained.

There are two versions of IUI:

1. Intrauterine insemination with partner sperm;
2. Intrauterine insemination with donor sperm.

IUI includes:

• The doctor may recommend fertility medication (if it is necessary) before the procedure to stimulate ovulation. During this process doctor will monitor the maturity of the follicles with blood tests and ultrasound.
• The semen samples processed by washing, centrifugation and migration in order to separate higher percent motile spermatozoa with normal morphology.
• Placing washed sperm directly into the uterine cavity around the time that ovulation is occurring using a thin, soft catheter.
• In some cases after IUI treatment the progesterone may be administrated to help the corpus luteum function.